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Journal Club Summary Methodology Score: 2/5                  Usefulness Score: 3.5/5 Zahed R, Moharamzadeh P, Alizadeharasi S, Ghasemi A, Saeedi M.Am J Emerg Med.2013 Sep;31(9):1389-92 Abstract Link This single centre, ED based, parallel group randomized control trial found that the topical application of an injectable form of tranexamic acid (TXA) was betterRead More →

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Journal Club Summary Methodology Score: 3.5/5               Usefulness Score: 3.5/5 Quant EC, Jeste SS, Muni RH, Cape AV, Bhussar MK, Peleg AY. BMJ. 2009 Sep 7;339:b3354. doi: 10.1136/bmj.b3354. Article Link This meta-analysis of randomized controlled trials comparing the use of steroids alone vs steroids and antivirals in the treatment of Bell’sRead More →

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Journal Club Summary Methodology Score: 3.5/5                          Usefulness Score: 3/5   Than M, Aldous S, Lord SJ, Goodacre S, Frampton CM, Troughton R, George P, Florkowski CM, Ardagh M, Smyth D, Jardine DL, Peacock WF, Young J, Hamilton G, Deely JM, Cullen L, Richards AM. JAMA Intern Med. 2013 Oct 7.Read More →

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Journal Club Summary Methodology Score: 4.5/5                          Usefulness Score: 4/5 Perry JJ, Stiell IG, Sivilotti ML, Bullard MJ, Hohl CM, Sutherland J, Émond M, Worster A, Lee JS, Mackey D, Pauls M, Lesiuk H, Symington C, Wells GA. JAMA. 2013;310(12):1248-1255. Abstract Link    This multicentre prospective validation cohort study found that the 3Read More →

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Journal Club Summary Methodology Score: 4/5                 Usefulness Score: 2.5/5   Mentzelopoulos SD, et al. JAMA. 2013;310(3):270-279. Article Link   This randomized, multi-centered, double blind, placebo controlled trial compared vasopressin, steroids and epinephrine (VSE) vs. epinephrine for in-hospital cardiac arrest and found a 18% ARR in favour of the VSE group forRead More →

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Journal Club Summary Landmark Series Methodology Score: 4/5                 Usefulness Score: 4/5 De Backer D, Biston P, Devriendt J, Madl C, Chochrad D, Aldecoa C, Brasseur A, Defrance P, Gottignies P, Vincent JL; SOAP II Investigators. N Engl J Med. 2010 Mar 4;362(9):779-89  Article Link   This pragmatic, blinded, randomized, multicenterRead More →

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Journal Club Summary Methodology Score: 4/5                 Usefulness Score: 3.5/5   Leuppi JD, Schuetz P, Bingisser R, Bodmer M, Briel M, Drescher T, et al. JAMA. 2013 Jun 5;309(21):2223-31 Article Link   This multicentre, Swiss-based RCT adds to the literature that suggests a short course (5days) of glucocorticoid is as effectiveRead More →

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Journal Club Summary Landmark Article Series – UPDATE   Methodology Score: 2.5/5              Usefulness Score: 4/5 Straus SE, Thorpe KE, Holroyd-Leduc J. JAMA. 2006 Oct 25;296(16):2012-22.   Article Link   This overview article from the JAMA Rational Clinical Exam series showed a non-significant trend towards a decrease in post-LP headaches whenRead More →

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Journal Club Summary Methodology Score: 4/5                 Usefulness Score: 3/5   Than M, Cullen L, Reid CM, Lim SH, Aldous S, Ardagh MW, et al. Lancet. 2011 Mar 26;377(9771):1077-84.  Abstract Link    This prospective multicentre cohort study attempted to validate a new 2 hour accelerated diagnostic protocol to allow rapid dischargeRead More →

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Journal Club Summary Methodology Score: 3/5                 Usefulness Score: 2/5   Chan EW, Taylor DM, Knott JC, Phillips GA, Castle DJ, Kong DC. Ann Emerg Med. 2013 Jan;61(1):72-81   Abstract Link   This randomized, double-blind, double dummy study comparing olanzepine plus midazolam or droperidol plus midazolam suggested these combinations were moreRead More →