Journal Club Summary Methodology Score: 4/5 Usefulness Score: 2/5 Karlow N, et al. Acad Emerg Med. 2018 Oct;25(10):1086-1097. Question and Methods: This was a systematic review and meta-analysis of low dose ketamine (LDK 0.3 – 0.5mg/kg) vs opioids for acute pain management in the ED. Findings: 3 studies were included suggesting LDKRead More →
Journal Club Summary Methodology: 4/5 Usefulness: 2.5/5 Meltzer AC, et al. JAMA Intern Med. 2018 Aug 1;178(8):1051-1057. Editorial: Medical Expulsive Therapy for Ureteral Stones – Stone Age Medicine. Methods: This multi-center RCT of emergency department patients presenting with symptomatic renal colic compared Tamsulosin vs placebo in the rate of stone passage at 28Read More →
Journal Club Summary Methodology Score: 3/5 Usefulness Score: 2/5 Atkinson PR, et al. Ann Emerg Med. 2018 Oct;72(4):478-489 Question and Methods: This was the first multicenter, prospective, RCT examining the effect of POCUS on 30-day survival of undifferentiated hypotensive patients presenting to ED. Findings: There was no important survival benefit with theRead More →
Methodology Score: 2.5/5 Usefulness Score: 2.5/5 Little P, et al. BMJ. 2017 May 22;357:j2148. Editorial: Controlling antibiotic prescribing for lower respiratory tract infections Scott AM et al. BMJ. 2017 May 22;357:j2398. doi: 10.1136/bmj.j2398. Question and Methods: This is a large, prospective, observational study of ambulatory patients with acute cough treated with no, immediateRead More →
Journal Club Summary Methodology: 4/5 Usefulness: 4/5 Kent AP, et al. J Am Coll Cardiol. 2018 Jul 17;72(3):255-267 Question and Methods: This was a post hoc analysis of the RE-LY trial examining the risk of NSAID use in patients receiving oral anticoagulation (OAC) for atrial fibrillation. Findings: NSAID use wasRead More →
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 5/5 Nogueira RG, et al. N Engl J Med. 2018 Jan 4;378(1):11-21 Editorial: A New DAWN for Imaging-Based Selection in the Treatment of Acute Stroke. Questions and Methods: DAWN was an open-label multi-centre RCT assessing functional outcomes of embolectomy compared with standardRead More →
Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 4/5 Johnston SC, et al. N Engl J Med. 2018 Jul 19;379(3):215-225 Editorial: Antiplatelet Therapy after Ischemic Stroke or TIA. Question and Methods: This randomized, double-blind trial evaluated ASA + Clopidogrel (DAPT) against ASA alone for preventing ischemic events after a minor stroke/high-risk TIA.Read More →
Journal Club Summary Methodology: 4/5 Usefulness: 4/5 Kuppermann N, et al. N Engl J Med. 2018 Jun 14;378(24):2275-2287. Editorial: Fluid Composition, Infusion Rate, and Brain Injury in Diabetic Ketoacidosis. Question and Methods: 13 centre RCT with four arms to determine the impact of fluid resuscitation rate and type on development ofRead More →
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 5/5 Nath S, et al. Lancet. 2018 Mar 24;391(10126):1197-1204 Question and Methods: This meta-analysis sought to determine, in lumbar punctures, whether atraumatic or conventional (traumatic) spinal needles were superior in terms of their complication rates. Findings: Atraumatic spinal needles were superior to conventional needlesRead More →
Journal Club Summary: A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest Methodology Score: 4/5 Usefulness Score: 3.5/5 Perkins GD, et al N Engl J Med. 2018 Jul 18. Editorial: Testing Epinephrine for Out-of-Hospital Cardiac Arrest. Callaway CW, et al. N Engl J Med. 2018 Jul 18. Question and Methods: Multicenter, randomized,Read More →