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In: Full Article, Neurosurgery, Trauma

Methodology: 3.5/5 Usefulness: 3.5/5 The CRASH-3 trial collaborators. The Lancet. 2019 Oct 14. Online First Editorial: CRASH-3: a win for patients with traumatic brain injury Question and Methods: Multi-centre, randomized, placebo-controlled trial looking at whether TXA (1g over 10 minutes followed by infusion over 8 hours) reduces mortality in patientsRead More →

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In: Journal Club, Orthopedics, Orthopedics, Trauma

Methodology: 4/5 Usefulness: 3.5/5 Kortekangas T, et al. BMJ. 2019 Jan 23;364:k5432 Question and Methods: This is a pragmatic, randomized, controlled trial to determine if 3 weeks of immobilization (in cast or orthosis) is non-inferior to usual treatment (6 weeks cast immobilization) for stable Weber B ankle fractures Findings: ImmobilizationRead More →

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In: ENT, Journal Club

Methodology Score: 2.5/5 Usefulness Score: 2.5/5 Akkan S, et al. Ann Emerg Med. 2019 Jul;74(1):72-78 Question and Methods: Prospective RCT comparing compression with saline, compression with tranexamic acid, and nasal packing with merocel for anterior epistaxis. Findings: No difference in 15-minute bleeding cessation for TXA (91.1%) or packing (93.3%), v/s saline (71.1%).  Lower 24hRead More →

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In: cardiac arrest, Cardiology, Journal Club, Resuscitation

Methodology Score: 4.5/5 Usefulness Score: 3.5/5 Lemkes JS, et al. N Engl J Med. 2019 Apr 11;380(15):1397-1407. Editorial: Coronary Angiography after Cardiac Arrest – The Right Timing or the Right Patients? Question and Methods: Patients with out-of-hospital cardiac arrest (OHCA) and shockable rhythm, but without STEMI on ECG following ROSCRead More →

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In: Journal Club, Radiology, Trauma

Methodology: 2/5 Usefulness: 2.5/5 Macri F, Greffier J, Khasanova E, Claret PG, Bastide S, Larbi A, Bobbia X, Pereira FR, de la Coussaye JE, Beregi JP. Ann Emerg Med. 2019 Jun;73(6):665-670.  Question and Methods: This 160-patient pilot study prospectively compared ultra-low dose CT chest and CXR to routine CT chest in minor bluntRead More →

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In: Infectious Disease, Journal Club, Respirology

Journal Club Summary Methodology Score: 2.5/5 Usefulness Score: 3/5 Prins HJ, et al. Eur Respir J. 2019 May 23;53(5).  Question and Methods: The CATCH Study was a multicentre, randomised, controlled open intervention clinical trial comparing CRP guided antibiotics for COPDE vs the Gold Strategy Findings: The study had a 14.5%Read More →

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In: Journal Club, Neurology

Journal Club Summary Methodology: 3.5/5 Usefulness: 2.5/5 Ma H, et al N Engl J Med. 2019 May 9;380(19):1795-1803 Editorial: Image-Guided Intravenous Alteplase for Stroke – Shattering a Time Window.  Question and Methods: This was an international, multicenter, randomized, placebo-controlled trial of intravenous tPA in patients with stroke who presented 4.5-9 hours afterRead More →

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In: Orthopedics, Orthopedics

Journal Club Summary Pellatt R, et al. Ann Emerg Med. 2019 Mar 7. pii: S0196-0644(19)30059-9.  Methodology Score: 3/5 Usefulness Score: 3.5/5 Question and Methods: Randomized control trial of 97 adult emergency department patients comparing buddy taping vs. ulnar gutter splinting, in acute, uncomplicated neck of 5th metacarpal (Boxer) fractures. Findings: At 12 weeksRead More →

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In: Airway, Anesthesiology, Critical Care, Journal Club, Resuscitation

Journal Club Summary Casey JD, et al. N Engl J Med. 2019 Feb 28;380(9):811-821. Methodology Score:  3.5/5 Usefulness Score: 3.5/5 Question and Methods: Multicenter, unblinded RCT in 7 ICUs comparing rates of hypoxia in patients undergoing BVM vs no ventilation during the period between induction and laryngoscopy. Findings: Compared to no ventilationRead More →