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Journal Club Summary Methodology Score: 3/5                  Usefulness Score: 3/5   Sharp AL, Vinson DR, Alamshaw F, Handler J, Gould MK. Ann Emerg Med. 2015 Aug 27. pii: S0196-0644(15)00616-2. Abstract Link Retrospective study of 31,094 patients investigated for PE, evaluating a traditional D-Dimer of < 500, less than 1000 and an age-adjusted cutoffRead More →

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In: Grand Round Summaries, Toxicology

Acute alcohol intoxication and alcoholism are two separate and unique entities that we see regularly in the emergency department. As ER physicians, our role for the acutely intoxicated patient should focus on ruling out life threatening disease and ensuring their safety for discharge.   Alcoholism, however, does predispose patients toRead More →

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Journal Club Summary Methodology Score: 3/5                  Usefulness Score: 2/5   Moler FW, Silverstein FS, Holubkov R, et al. N Engl J Med. 2015 May 14;372(20):1898-908. Full Article    This prospective, multi-center RCT found no significant difference in functional outcomes between hypo- and normo-thermic management following out of hospital arrest, although a clinicalRead More →

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Journal Club Summary Methodology Score: 4.5/5               Usefulness Score: 4.5/5   Appelboam A, Reuben A, Mann C, et al. Lancet. 2015 Aug 24. pii: S0140-6736(15)61485-4. Full Article The REVERT trial, a pragmatic, multicenter RCT evaluating the efficacy of a modified Valsalva maneuver (supine positioning and passive leg elevation after Valsalva strain) vsRead More →

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Journal Club Summary Methodology Score: 3/5      Usefulness Score: 2/5   Reichlin T, Twerenbold R, Wildi K, et al. CMAJ May 19, 2015 187:E243–E252; Full Article    This multicenter study aiming to prospectively validate a 1 hour algorithm using a high sensitivity cardiac troponin assay classified 59.5% patients in the Rule OutRead More →

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Journal Club Summary Methodology Score: 4.5/5               Usefulness Score: 4.5/5   Pecard R, Starr K, MacLennan G, Lam T, et al. Published Online May 19, 2015 http://dx.doi.org/10.1016/S0140-6736(15)60933-3 Full Article   This high quality multicenter, randomized, triple-blind, placebo-controlled study of almost 1,200 adult patients with CT confirmed solitary ureteral stone (<10mm) found no statisticallyRead More →

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Journal Club Summary Methodology Score: 3.5/5 Usefulness Score:  3/5   Arora S, Burner E, Terp S, Nok Lam C, Nercisian A, Bhatt V, Menchine M. Acad Emerg Med. 2015 Jan;22(1):31-7. Full Article   In this single-center, open label RCT of 374 patients, a per-protocol analysis demonstrated that text message appointment reminders improvedRead More →

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Journal Club Summary Methodology Score: 3/5                  Usefulness Score: 2.5/5   Rahimi RS, Singal AG, Cuthbert JA, Rockey DC. JAMA Intern Med. 2014 Nov;174(11):1727-33 Full Article Editorial:  Polyethylene Glycol for Hepatic Encephalopathy Polyethylene A New Solution to Purge an Old Problem? Doran AE, Shah NL JAMA Intern Med. 2014;174(11):1734-1735 Editorial Link   This small,Read More →