Journal Club Summary Landmark Series Sprung CL, Annane D, Keh D, Moreno R, Singer M, Freivogel K, et al. N Engl J Med. 2008 Jan.10;358(2):111–24. Article Link This European multicentre RCT compared hydrocortisone to placebo for 499 ICU patients with septic shock and found no difference in mortality despite quickerRead More →
Journal Club Summary Landmark Series Margaretten ME, Kohlwes J, Moore D, Bent S. JAMA. 2007Apr.4;297(13):1478–88. Article Link This systematic overview from the excellent JAMA series reviewed the relatively weak evidence regarding assessment of patients with suspected septic arthritis. JC attendees found the odds ratios for clinical findings to be usefulRead More →
Journal Club Summary Landmark Series Clark E, Plint AC, Correll R, Gaboury I, Passi B. A Pediatrics. 20 07Mar.1;119(3):460–7. Article Link This high quality RCT by local investigators rigorously compared acetaminophen, ibuprofen and codeine analgesics among children in the ED with MSK trauma and found ibuprofen to be statistically and clinically significantlyRead More →
Journal Club Summary Landmark Series Straus SE, Thorpe KE, Holroyd-Leduc J. JAMA. 2006Oct.25;296(16):2012–22. PubMed Link This systematic literature review and meta-analysis in the Rational Clinical Examination series found a non-significant trend towards less post-LP headache with the use of atraumatic needle and mobilization post-LP. Reinsertion of the stylet significantly reducedRead More →
Journal Club Summary Landmark Series Andrew K Chang, Polly E Bijur, Robert H Meyer, Mark K Kenny, Clemencia Solorzano, and E John Gallagher PubMed Link This U.S. randomized trial in ED adults with severe pain found similar effectiveness for intravenous hydromorphone [0.015 mg/kg] and iv morphine [0.1 mg/kg]. ThisRead More →
Journal Club Summary Landmark Series Levitan RM, Kinkle WC, Levin WJ, Everett WW. Ann Emerg Med. 2006 Jun.;47(6):548–55. PubMed Link This U.S. study evaluated manipulation techniques for direct laryngoscopy during endotracheal intubation in 1,530 comparisons performed by 104 physicians in fresh cadavers. Bimanual laryngoscopy improved laryngeal view compared to cricoid pressure,Read More →
Journal Club Summary Methodology: 4.5/5 Usefulness: 4/5 Stiell IG, Nichol G, Leroux BG, Rea TD, Ornato JP, Powell J, Christenson J, Callaway CW, Kudenchuk PJ, Aufderheide TP, Idris AH, Daya MR, Wang HE, Morrison LJ, Davis D, Andrusiek D, Stephens S, Cheskes S, Schmicker RH, Fowler R, Vaillancourt C, HostlerRead More →
Journal Club Summary Methodology: 2/5 Usefulness: 3/5 Lotrionte M, Biondi-Zoccai G, Imazio M, Castagno D, Moretti C, Abbate A, Agostoni P, Brucato AL, Di Pasquale P, Raatikka M, Sangiorgi G, Laudito A, Sheiban I, Gaita F. Am Heart J. 2010 Oct;160(4):662-70. Review Article Link This study was a systematicRead More →
Journal Club Summary Methodology: 4/5 Usefulness: 4.5/5 Lees KR, Bluhmki E, von Kummer R, Brott TG, Toni D, Grotta JC, Albers GW, Kaste M, Marler JR, Hamilton SA, Tilley BC, Davis SM, Donnan GA, Hacke W; ECASS, ATLANTIS, NINDS and EPITHET rt-PA Study Group, Allen K, Mau J, Meier D,Read More →
Journal Club Summary Methodology: 3.5/5 Usefulness: 2/5 Jalili M, Fathi M, Moradi-Lakeh M, Zehtabchi S. Ann Emerg Med. 2012 Apr;59(4):276-80. PubMed Link This double blind, double dummy RCT compared sublingual Buprenorphine (0.4 mg) to IV Morphine (5 mg) for acute pain in adults presenting to the ED with acuteRead More →