
Defibrillation Strategies for Refractory Ventricular Fibrillation
Methodology: 4.5/5 Usefulness: 4.5/5 Cheskes S, et al. N Engl J Med. 2022 Nov 6. Question and Methods: A cluster-randomized open-label trial evaluating survival... Read more.

Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis
Methodology: 4/5 Usefulness: 4/5 de-Madaria E, et al. N Engl J Med. 2022 Sep 15;387(11):989-1000. Question and Methods: A multicenter, open-label, randomized control... Read more.

Resuscitation with blood products in patients with trauma-related haemorrhagic shock receiving prehospital care (RePHILL): a multicentre, open-label, randomised, controlled, phase 3 trial
Methodology: 4/5 Usefulness: 3/5 Crombie N, et al. Lancet Haematol. 2022 Apr;9(4):e250-e261. Question and Methods: Multicenter RCT investigating prehospital resuscitation... Read more.

Non-sterile gloves and dressing versus sterile gloves, dressings and drapes for suturing of traumatic wounds in the emergency department: a non-inferiority multicentre randomised controlled trial
Methodology: 4/5 Usefulness: 3.5/5 Zwaans JJM, et al. Emerg Med J. 2022 Sep;39(9):650-654. Question and Methods: This study assessed non-inferiority between sterile... Read more.

Restriction of Intravenous Fluid in ICU Patients with Septic Shock
Methodology: 4/5 Usefulness: 3/5 Meyhoff TS, et al. N Engl J Med. 2022 Jun 30;386(26):2459-2470. Question and Methods: International, stratified, parallel group,... Read more.

Acetazolamide in Acute Decompensated Heart Failure with Volume Overload
Methodology Score: 4/5 Usefulness Score: 2/5 (Emergency) 4/5 (Internal medicine) Mullens W, et al. N Engl J Med.... Read more.

Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest
Methodology: 4/5 Usefulness: 4/5 Kjaergaard J, et al. N Engl J Med. 2022 Oct 20;387(16):1456-1466. Question and Methods: This was a double-blind, randomized trial... Read more.

Accuracy of Ultrasound Jugular Venous Pressure Height in Predicting Central Venous Congestion
Methodology: 3/5 Usefulness: 1.5/5 Wang L, et al. Ann Intern Med. 2022 Mar;175(3):344-351. Question and Methods: Using a convenience sample of 100 patients out... Read more.

Intranasal Topical Application of Tranexamic Acid in Atraumatic Anterior Epistaxis: A Double-Blind Randomized Clinical Trial
Methodology: 4/5 Usefulness: 4/5 Hosseinialhashemi M, et al. Ann Emerg Med. 2022 Sep;80(3):182-188. doi: 10.1016/j.annemergmed.2022.04.010. Question and methods:... Read more.

Immobilisation of torus fractures of the wrist in children (FORCE): a randomised controlled equivalence trial in the UK.
Methodology: 4/5 Usefulness: 4.5/5 Perry DC, et al. Lancet. 2022 Jul 2;400(10345):39-47. Question and Methods: This large, multicentre, pragmatic RCT aimed to show... Read more.