Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension
Methodology: 4/5 Usefulness: 3/5 National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury Clinical Trials Network; et al. N... Read more.
Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest
Methodology: 4/5 Usefulness: 2.5/5 Suverein MM, et al. N Engl J Med. 2023 Jan 26;388(4):299-309. doi: 10.1056/NEJMoa2204511. Question and Methods: Does eCPR increase... Read more.
Risk of Traumatic Brain Injuries in Infants Younger than 3 Months With Minor Blunt Head Trauma
Methodology: 3/5 Usefulness: 3.5/5 Abid Z, et al. Ann Emerg Med. 2021 Sep;78(3):321-330.e1. Question and Methods: The study assessed the risk of brain injuries... Read more.
Dexamethasone and ketorolac compare with ketorolac alone in acute renal colic: A randomized clinical trial
Methodology: 2.5/5 Usefulness: 2.5/5 Razi A, et al. Am J Emerg Med. 2022 Aug;58:245-250. Question and Methods: This single-center, RCT of 120 patients with acute... Read more.
High-Sensitivity Cardiac Troponin on Presentation to Rule Out Myocardial Infarction: A Stepped-Wedge Cluster Randomized Controlled Trial
Methodology: 3.5/5 Usefulness: 3.5/5 Anand A, et al. Circulation. 2021 Jun 8;143(23):2214-2224. Raising the Bar for Clinical Cardiac Troponin Research Studies... Read more.
Defibrillation Strategies for Refractory Ventricular Fibrillation
Methodology: 4.5/5 Usefulness: 4.5/5 Cheskes S, et al. N Engl J Med. 2022 Nov 6. Question and Methods: A cluster-randomized open-label trial evaluating survival... Read more.
Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis
Methodology: 4/5 Usefulness: 4/5 de-Madaria E, et al. N Engl J Med. 2022 Sep 15;387(11):989-1000. Question and Methods: A multicenter, open-label, randomized control... Read more.
Resuscitation with blood products in patients with trauma-related haemorrhagic shock receiving prehospital care (RePHILL): a multicentre, open-label, randomised, controlled, phase 3 trial
Methodology: 4/5 Usefulness: 3/5 Crombie N, et al. Lancet Haematol. 2022 Apr;9(4):e250-e261. Question and Methods: Multicenter RCT investigating prehospital resuscitation... Read more.
Non-sterile gloves and dressing versus sterile gloves, dressings and drapes for suturing of traumatic wounds in the emergency department: a non-inferiority multicentre randomised controlled trial
Methodology: 4/5 Usefulness: 3.5/5 Zwaans JJM, et al. Emerg Med J. 2022 Sep;39(9):650-654. Question and Methods: This study assessed non-inferiority between sterile... Read more.
Restriction of Intravenous Fluid in ICU Patients with Septic Shock
Methodology: 4/5 Usefulness: 3/5 Meyhoff TS, et al. N Engl J Med. 2022 Jun 30;386(26):2459-2470. Question and Methods: International, stratified, parallel group,... Read more.